Adolescents who were born very preterm have decreased brain volumes

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Adolescents who were born very preterm have decreased brain volumes.

Infants born very preterm have an increased risk of brain injury. Given the great increase in the number of such infants that are surviving, it is important to establish whether any resultant brain abnormalities persist into adolescence and adult life. We therefore examined in vivo whole brain, grey matter, white matter and hippocampal volumes, ventricular size and grey/white matter ratios in a...

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Personality in Adults Who Were Born Very Preterm

AIM To investigate the personality in very preterm individuals (VPT; gestational age, GA, <32 weeks) at adult age in two cohorts born in 1974-76 and 1980-82, respectively, and to illuminate the effect of increased survival rates and the clinical implications of deviations in personality. METHOD Demographic data were extracted for all individuals born in Denmark in 1974-76 and 1980-82. From ea...

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Subregional Hippocampal Morphology and Psychiatric Outcome in Adolescents Who Were Born Very Preterm and at Term

BACKGROUND The hippocampus has been reported to be structurally and functionally altered as a sequel of very preterm birth (<33 weeks gestation), possibly due its vulnerability to hypoxic-ischemic damage in the neonatal period. We examined hippocampal volumes and subregional morphology in very preterm born individuals in mid- and late adolescence and their association with psychiatric outcome. ...

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Functional Neuroanatomy of Executive Function after Neonatal Brain Injury in Adults Who Were Born Very Preterm

Individuals who were born very preterm (VPT; <33 gestational weeks) are at risk of experiencing deficits in tasks involving executive function in childhood and beyond. In addition, the type and severity of neonatal brain injury associated with very preterm birth may exert differential effects on executive functioning by altering its neuroanatomical substrates. Here we addressed this question by...

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Altered resting-state functional connectivity in emotion-processing brain regions in adults who were born very preterm

BACKGROUND Very preterm birth (VPT; <32 weeks of gestation) has been associated with impairments in emotion regulation, social competence and communicative skills. However, the neuroanatomical mechanisms underlying such impairments have not been systematically studied. Here we investigated the functional integrity of the amygdala connectivity network in relation to the ability to recognize emot...

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ژورنال

عنوان ژورنال: Brain

سال: 2002

ISSN: 1460-2156

DOI: 10.1093/brain/awf157